β -Lactam Antibiotics

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Chapter: Pharmaceutical Microbiology : Antibiotics And Synthetic Antimicrobial Agents: Their Properties And Uses

For 20 years after their introduction, the penicillins were the only category of β-lactam antibiotics. They were joined, in the mid 1960s, by the cephalosporins, and towards the end of the 20th century by carbapenems and monobactams.


β -LACTAM ANTIBIOTICS


For 20 years after their introduction, the penicillins were the only category of β-lactam antibiotics. They were joined, in the mid 1960s, by the cephalosporins, and towards the end of the 20th century by carbapenems and monobactams. These antibiotics all have the same mechanism of antibacterial action and all possess the β-lactam ring as an integral part of their structure, but they differ widely in other characteristics.

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