Analysis of semisolid dosage forms

| Home | | Pharmaceutical Drugs and Dosage | | Pharmaceutical Industrial Management |

Chapter: Pharmaceutical Drugs and Dosage: Semisolid dosage forms

The following quality attributes of semisolid dosage forms of drugs, such as ointments and creams, are evaluated:


Analysis of semisolid dosage forms

The following quality attributes of semisolid dosage forms of drugs, such as ointments and creams, are evaluated:

1.        Physical stability, in terms of nonseparation of emulsion phases, when applicable, and homogeneity of appearance/color.

2.        Drug identity, purity, content, and uniformity of content. The content of drug per unit mass of the dosage form and impurities/related sub-stances of the drug substance indicate its potency and purity.

3.        Drug release rate using an in vitro test.

4.        Viscosity of the formulation.

5.        Minimum fill in the container and deliverable volume or doses.

6.        Although these dosage forms are not required to be sterile, the micro-bial content of certain bacterial species, such as Staphylococcus aureus and Pseudomonas aeruginosa, is controlled.

Contact Us, Privacy Policy, Terms and Compliant, DMCA Policy and Compliant

TH 2019 - 2022 pharmacy180.com; Developed by Therithal info.