Benzoxazocine Derivative

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Chapter: Essential pharmacology : Nonsteroidal Anti-inflammatory Drugs And Antipyreticanalgesics

Nefopam : It is a nonopioid analgesic which does not inhibit PG synthesis and acts rapidly in traumatic and postoperative pain. Favourable results have been obtained in short lasting musculoskeletal pain.


BENZOXAZOCINE DERIVATIVE

 

Nefopam

 

It is a nonopioid analgesic which does not inhibit PG synthesis and acts rapidly in traumatic and postoperative pain. Favourable results have been obtained in short lasting musculoskeletal pain.

 

Nefopam produces anticholinergic (dry mouth, urinary retention, blurred vision) and sympathomimetic (tachycardia, nervousness) side effects, and nausea is often dose limiting. It is contraindicated in epileptics.

 

Dose: 30–60 mg TDS oral, 20 mg i.m. 6 hourly.

 

NEFOMAX 30 mg tab, 20 mg in 1 ml amp.

 

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