Conclusion

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Chapter: Pharmacovigilance: PEM in the UK

Prescription–event monitoring (PEM) is a valuable and well-established method of hypothesis-generating pharmacovigilance.


CONCLUSION

Prescription–event monitoring (PEM) is a valuable and well-established method of hypothesis-generating pharmacovigilance. Its use since 1984 has produced a substantial database which itself forms an important research tool. PEM has found its own place in phar-macovigilance and is at its best in monitoring drugs receiving widespread, long-term GP use. The method lends itself to validation of individual case reports and allows the data to be explored by well-established epidemiological and clinical research techniques.

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