Immunotherapy

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Chapter: Medicinal Chemistry : Antineoplastic Agents

Antineoplastic Agents : Immunotherapy - Interferons


Antineoplastic Agents - SYNTHESIS AND DRUG PROFILE

Immunotherapy

Interferons

The interferons are a family of cytokines with broad-spectrum antiviral and anticancer activity making them biological responsive modifiers. Three types of naturally occurring interferons have been found:

1.           Leukocytic interferons: Interferons α produced by lymphocytes and macrophages.

2.           Fibroblast interferons: Interferons β produced by fibroblast epithelial cell and macrophages.

3.           Immune interferons: Interferons γ synthesized by CD4+, CD8+, and natural killer lymphocytes.

 

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