Local drug delivery to the lung

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Chapter: Pharmaceutical Drugs and Dosage: Organ-specific drug delivery

Pulmonary route has long been utilized for localized drug delivery to the lung, which helps overcome several barriers to the treatment of lung disorders such as systemic side effects and metabolism, while allowing high local concentrations and rapid clinical response.


Local drug delivery to the lung

Pulmonary route has long been utilized for localized drug delivery to the lung, which helps overcome several barriers to the treatment of lung disorders such as systemic side effects and metabolism, while allowing high local concentrations and rapid clinical response. In many cases, the dose of the drug required for local treatment can be significantly reduced. For example, orally administered salbutamol at 2–4 mg of dose is therapeutically equiva-lent to 100–200 μg of salbutamol administered directly into the lung.

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