Midazothiazoles

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Chapter: Medicinal Chemistry : Anthelmintics

Midazothiazoles: Levamisole (Bizole, Vermisol) - Synthesis and Drug Profile


Anthelmintics - Synthesis and Drug Profile

Midazothiazoles

 

Levamisole (Bizole, Vermisol)


Synthesis:


Mode of action: It stimulates the ganglion in the worms, causes tonic paralysis, which results in the expulsion of live worms. These also interfere with the carbohydrate metabolism by inhibiting fumarate reductase.

Dose: The administered dose is 15 mg as a single dose, repeated after 1 month to prevent recurrence.

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