Narcotic antagonists

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Chapter: Medicinal Chemistry : Narcotic Analgesics

Prevents or abolishes excessive respiratory depression caused by the administration of morphine or related compounds. They act by competing for the same analgesic receptor sites.


NARCOTIC ANTAGONISTS

The euphoria accompanying with use of heroin and other narcotics reinforces repeated drug-seeking behaviour as psychological dependence develops. Once tolerance develops, the opiate-dependent individual avoids painful withdrawal symptoms by continuously increasing the amounts of opiate consumed.

Narcotic antagonists: Prevents or abolishes excessive respiratory depression caused by the administration of morphine or related compounds. They act by competing for the same analgesic receptor sites. They are structurally related to morphine with the exception of the group attached to nitrogen.


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