Negative Feedback Mechanism

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Chapter: Anatomy, Physiology And Health Education : Homeostasis

Negative feedback is the one to which the system reacts in such a way as to arrest the change or reverse the direction of change. After receiving a message, effectors send negative feedback signals back to the system. Now, the system stabilizes its own function and makes an attempt to maintain homeostasis.


NEGATIVE FEED BACK

 

Negative feedback is the one to which the system reacts in such a way as to arrest the change or reverse the direction of change. After receiving a message, effectors send negative feedback signals back to the system. Now, the system stabilizes its own function and makes an attempt to maintain homeostasis.

 

 


 

 

Many homeostatic mechanisms in the body function through negative feedback. For example, thyroid-stimulating hormone (TSH) released from pituitary gland stimulates thyroid gland to secrete thyroxine. When thyroxine level increases in blood, it inhibits the secretion of TSH from pituitary so that, the secretion of thyroxin from thyroid gland decreases (Fig. 4.2). On the other hand, if thyroxine secretion is less, its low blood level induces pituitary gland to release TSH. Now, TSH stimulates thyroid gland to secrete thyroxine (Refer Chapter 67 for details). Another example for negative feedback mechanism is maintenance of water balance in the body.

 

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