Preparations and Dose of Testosterone

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Chapter: Essential pharmacology : Androgens and Drugs for Erectile Dysfunction

Testosterone (free): 25 mg i.m. daily to twice weekly; AQUAVIRON 25 mg in 1 ml inj.


PREPARATIONS AND DOSE

 

1. Testosterone (free): 25 mg i.m. daily to twice weekly; AQUAVIRON 25 mg in 1 ml inj.

 

2. Testosterone propionate: 25–50 mg i.m. daily to twice weekly: TESTOVIRON, PARENDREN, TESTANON 25, 50 mg/ml inj.

 

3. TESTOVIRON DEPOT 100: testo. propionate 25 mg + testo. enanthate 100 mg in 1 ml amp; 1 ml i.m. weekly.

 

4. TESTOVIRON DEPOT 250: testo. propionate 250 mg + testo. enanthate 250 mg in 1 ml amp; i.m. every 2–4 weeks.

 

5. SUSTANON ‘100’: testo. propionate 20 mg + testo. phenyl propionate 40 mg + testo. isocaproate 40 mg in 1 ml amp; 1 ml i.m. every 2–3 weeks.

 

6. SUSTANON ‘250’: testo. propionate 30 mg + testo. phenylpropionate 60 mg + testo. isocaproate 60 mg + testo. decanoate 100 mg in 1 ml amp; 1 ml i.m. every 3–4 weeks.

 

7. NUVIR: Testosterone undecanoate 40 mg cap, 1–3 cap daily for male hypogonadism, osteoporosis.

8. Mesterolone: Causes less feedback inhibition of Gn secretion and spermatogenesis; PROVIRONUM, MESTILON 25 mg tab; 1–3 tab daily for androgen deficiency.

 

Transdermal Androgen

 

Recently delivery of androgen across skin has been achieved by developing suitable solvents and absorption facilitators. By cutaneous delivery, testosterone/dihydrotestosterone circumvent hepatic first pass metabolism; uniform blood levels are produced round the clock. A gel formulation has been marketed for once daily application in hypogonadism and impotence.

 

ANDRACTIM: Dihydrotestosterone 25 mg/g gel (100 g tube); 5–10 g gel to be applied over nonscrotal skin once daily.

 

Fixed dose combinations of testosterone with yohimbine, strychnine and vitamins are banned in India.

 

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