Prevention of Adverse Effects to Drugs

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Chapter: Essential pharmacology : Adverse Drug Effects

Adverse drug effects can be minimized but not altogether eliminated by observing the following practices:


PREVENTION OF ADVERSE EFFECTS TO DRUGS

 

Adverse drug effects can be minimized but not altogether eliminated by observing the following practices:

 

§  Avoid all inappropriate use of drugs in the context of patient’s clinical condition.

§  Use appropriate dose, route and frequency of drug administration based on patient’s specific variables.

§  Elicit and take into consideration previous history of drug reactions.

§  Elicit history of allergic diseases and exercise caution (drug allergy is more common in patients with allergic diseases).

§  Rule out possibility of drug interactions when more than one drug is prescribed.

§  Adopt correct drug administration technique (e.g. intravenous injection of vancomycin must be slow).

§  Carry out appropriate laboratory monitoring (e.g. prothrombin time with warfarin, serum drug levels with lithium).

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