Pharmaceutical Drugs and Dosage: Pharmaceutical solutions - Review questions answers
Review questions
18.1 Indicate
which statements are TRUE and which are FALSE.
A. Buffers are used to
avoid fluctuations in the pH of a solution
B. Tinctures and
elixirs contain alcohol, whereas syrups contain sucrose
C. Concentrated sucrose
solutions are good for microbial growth, but not the diluted sucrose solution.
D. Pharmacologically
active agents should be in solution before they can exert their effect.
E. In general, solution
dosage forms have a longer shelf life than the same drug formulated as a
tablet.
18.2 Which of
the following describes the solution dosage form?
A. A homogeneous system
B. The product contains
at least two components
C. The solute is in a
monomolecular dispersion
D. All of the above
E. None of the above
18.3 Define
the following terminologies: pharmaceutical solutions, syrups, elixirs, spirits, and
tinctures.
18.4 Which of
the following formulation components are antimicrobial preservatives?
A. Sodium benzoate
B. Methylparaben
C. Propylparaben
D. All of the above
E. B and C of the above
18.5 Which of
the following characteristics will increase drug solubility in an aqueous solution?
A. Presence of a polar
group
B. Low melting point
C. High boiling point
D. Presence of an
ionized group
Answers:
18.1 A. True
B. True
C. False
D. True
E. False
18.2 A and C.
18.3 Pharmaceutical solutions are homogeneous mixtures
of one or more solutes
dispersed in a suitable solvent or a mixture of mutually mis-cible solvents:
·
Syrups are aqueous
solutions containing a sugar or sugar substi-tute with or without added
flavoring agents and drugs.
·
Elixirs are sweetened
hydroalcoholic (combinations of water and
ethanol) solutions.
·
Spirits are hydroalcoholic
solutions of aromatic materials.
·
Tinctures are alcoholic or
hydroalcoholic solutions of chemical or soluble
constituents of vegetable drugs.
18.4 D.
18.5 A, B, and D.
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