Review questions answers

| Home | | Pharmaceutical Drugs and Dosage | | Pharmaceutical Industrial Management |

Chapter: Pharmaceutical Drugs and Dosage: Parenteral drug products

Pharmaceutical Drugs and Dosage: Parenteral drug products - Review questions answers


Review questions

 

22.1 All parenteral products must be

A.      Sterile

B.      Pyrogen free

C.      Isotonic

D.      Sterile and pyrogen free

E.       All of the above

22.2 An intravenous injection is desirable when

A.      A rapid action is required

B.      An oral administration is ineffective

C.      A prolonged action is required

D.      A and B

22.3 Which of the following statements is TRUE and which one is FALSE?

A.      Systemic drug absorption occurs more rapidly than from oral administration compared to intravenous administration.

B.      All parenteral products must be isotonic.

C.      Filtration cannot be used to sterilize parenteral suspensions.

D.      Buffers are used in parenteral products to stabilize the solution against pH changes.

E.       Sterilization by filtration prevents thermal stress on the product.

F.       During aseptic filtration, the solution is passed through a sterile filter of 2 μm pore size.

G.      Filtration cannot be used to sterilize parenteral suspensions.

H.      Heat and radiation sterilization methods are intended to eliminate viable microorganism from the final products.

Answers:

22.1 D.

22.2 D. The bacterial endotoxin test determines the level of bacterial endo-toxin only from gram-positive bacteria. This test cannot determine the fever-producing potential of endotoxins. Gram-negative bacte-ria do not have to be alive for the endotoxin to produce an effect.

22.3 A. True

B. True

C. True

D. True

E. True

F. False

G. True

H. True

Contact Us, Privacy Policy, Terms and Compliant, DMCA Policy and Compliant

TH 2019 - 2022 pharmacy180.com; Developed by Therithal info.