SAR of Succinimides

| Home | | Medicinal Chemistry |

Chapter: Medicinal Chemistry : Anticonvulsants

The activity of antiepileptic agents, such as the oxazolidine 2,4-dione with substituted succinamides was logical choice for synthesis and evaluation.


SAR of Succinimides


  • The activity of antiepileptic agents, such as the oxazolidine 2,4-dione with substituted succinamides (CH2 replace O) was logical choice for synthesis and evaluation.

  • N-demethylation occurs to yield the putative active metabolite. Both phensuximide and the

N-demethyl metabolite are inactivated by p-hydroxylation and conjugation.


Contact Us, Privacy Policy, Terms and Compliant, DMCA Policy and Compliant

TH 2019 - 2022 pharmacy180.com; Developed by Therithal info.