Second-Generation Alkyl Amine Type Calcium Channel Blockers

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Chapter: Medicinal Chemistry : Antianginals

Antianginals : Second-Generation Alkyl Amine Type Calcium Channel Blockers : Bepridil - Synthesis and Drug Profile


SYNTHESIS AND DRUG PROFILE


Second-Generation Alkyl Amine Type Calcium Channel Blockers


i. Bepridil


Synthesis


Properties and uses: Bepridil exists as white crystals and is used as a vasodilator and antianginal agent.

Dose: The usual dose is 5 mg/kg.


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