Sutures and Ligatures

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Chapter: Pharmacognosy and Phytochemistry : Fibres, Sutures and Surgical Dressings

A surgical suture is a thread or sting used for sewing or stitching together tissues, muscles, and tendons with the help of a needle. If these threads or fibres are used to tie a blood vessel to stop bleeding without the use of a needle, then they are digested in animal tissues.


SUTURES AND LIGATURES

 

 

A surgical suture is a thread or sting used for sewing or stitching together tissues, muscles, and tendons with the help of a needle. If these threads or fibres are used to tie a blood vessel to stop bleeding without the use of a needle, then they are digested in animal tissues,for example, catgut, kangaroo tendon, and synthetic polyesters. If the sutures are not absorbed in the body, they are called nonabsorbable sutures, for example, silk, cotton, nylon, synthetic polyester fibres and stainless steel wire. A good quality of suture should be well-sterilized, nonirritant; having well-mechanical strength, fine gauze and with minimum time of absorption.

 

Absorbable Sutures

 

Surgical catgut

 

Catgut is a sterilized fibre or strand prepared from collagen of connective tissues obtained from healthy animals like sheep and cattle.

 

Preparation

 

The submucosal layer of small intestine of a freshly killed animal is used for the preparation of catgut. About 7.5 m long intestine is cleaned and split longitudinally into ribbons. The inner most mucosa and two outer layers of submucosa, muscularis, and serosal layers, are removed with the help of a machine leaving behind the submucosa. Up to six such ribbons are stretched, spun and dried to form a uniform strand. These fibres are polished to get smooth strings, gauzed for their diameter, cut into suitable lengths and sterilized by placing the catgut in glass tubes filled with anhydrous high-boiling liquids like toluene or xylene and then heating in an autoclave. Sterilization may be done by irradiating the suture by electron particles or by gamma rays from cobalt-60.

 

Kangaroo tendons, used in hernia and bone repairs, are prepared from the tails of kangaroo by the identical method adopted for the preparation of catgut, Chromicized surgical catguts are prepared by soaking the ribbons in solutions of chromium salts for tanning the tissues. These fibres are not affected by proteolytic enzymes in the body and they are not absorbed rapidly in the body.

 

Synthetic polyesters

 

The polymers obtained by condensation of cyclic derivatives of glycolic acid (glycolide) with cyclic derivatives of lactic acid (lacticide) are used to prepare synthetic absorbable sutures. These sutures have high tensile strength and are degraded by hydrolysis and absorbed in the tissue.

 

Nonabsorbable Sutures

 

Nonabsorbable sutures are not affected by the body fluid and remained unchanged for a long period. They are removed after healing of the wounds. Silk, cotton, nylon, and metallic sutures are classified as nonabsorbable sutures.

 

Silk sutures

 

Silk sutures are prepared by spinning or twisting silk fibres into a single strand of varying diameters. The sutures are smooth and strong and braided by combining several twisted yarns into a compact mass. The strands are sterilized and boiled with water to soften them.

 

Cotton sutures

 

Cotton sutures have uniform size and recommended in critical parts where strength of the sutures is required for long time.

 

Nylon sutures

 

The microfilaments of nylon are braided into strands of required diameter. These sutures are strong, water resistant, and used in skin and plastic surgery.

 

Linen suture

 

A linen suture is cheap, very strong under moist condition but not uniform in diameter.

 

Metallic sutures

 

Metallic wires of silver or stainless steel are used as surgical aid. These wires are available as mono-filaments, twists, and braids.

 

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