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Pharmaceutical Inorganic and Analytical Chemistry - Practical - Experimental laboratory pdf record
Pharmacy - Bachelor of Pharmacy (Bpharm) - 1st Semester - 1st Year - Subject/Practical Laboratory: Pharmaceutical Inorganic and Analytical Chemistry - Practical (BP111P) - laboratory Experimental Note Download PDF

BP111P:
Pharmaceutical
Inorganic and Analytical Chemistry (Practical)
COURSE OBJECTIVES:
The objectives of
this course are to:
1. Gain practical
knowledge on various volumetric titration techniques.
2. Learn the
principles of volumetric analysis.
3. Study the
preparation and assessment of inorganic compounds.
4. Determine the
assay of various inorganic compounds in pharmaceutical use.
5. Develop analytical
skill for the qualitative and quantitative analysis of various inorganic
compounds.
COURSE OUTCOMES
(CO):
Upon successful
completion of this course, the students will be able to:
1. Perform limit
tests to detect and identify impurities in pharmaceutical substances.
2. Prepare various
pharmaceutical inorganic compounds following standard procedures.
3. Analyze the
significance of quality control in pharmaceutical products and raw materials.
4. Demonstrate
proficiency in titrimetric analysis using different volumetric techniques.
5. Competence in
applying analytical skills to qualitative and quantitative data.
Detailed Syllabus:
List of practical
1. Limit tests (Any 4
Experiments) a. Limit test and modified limit test
for Chloride as per Indian Pharmacopoeia b. Limit test and modified limit test
for sulphate as per Indian Pharmacopoeia c. Limit test for Iron d. Limit test
for Lead e. Limit test for arsenic
2. Preparation of
inorganic pharmaceuticals (Any 3 Experiments) a.
Preparation of Aluminium hydroxide b. Preparation of potash alum c. Preparation
of ferrous sulphate
d. Preparation of
Magnesium sulphate from magnesium hydroxide or magnesium carbonate
3. Test for Purity
(Any 2 Experiments) a. Assessment of swelling power of bentonite as per Indian
Pharmacopoeia b. Evaluation of acid neutralizing capacity of aluminium
hydroxide gel c. Determination of potassium iodate and iodine in potassium
Iodide
4. Assay of the
following inorganic compounds including standardization of titrant (Any 5
Experiments) a. Assay of ammonium chloride by acid base titration, b. Assay of
Ferrous sulphate by Cerimetry, c. Assay of Copper sulphate by Iodometry, d.
Assay of Calcium gluconate by Complexometry, e. Assay of Hydrogen peroxide by
Permanganometry, f. Assay of Sodium benzoate by non-aqueous titration, g. Assay
of Sodium Chloride by precipitation titration (Modified Volhard’s method)
Recommended
References (Preferably Latest Editions):
1. Bentley, R. and
Driver, J., Bentley and Driver’s Textbook of Pharmaceutical Chemistry. Oxford:
Oxford University Press.
2. Vogel, A.I.,
Vogel’s Textbook of Quantitative Chemical Analysis. Essex: Pearson Education
Limited.
3. Beckett, A.H. and
Stenlake, J.B., Practical Pharmaceutical Chemistry. Part I & II. London:
The Athlone Press, University of London.
4. Kennedy, J.H.,
Analytical Chemistry: Principles. New York: Saunders College Publishing.
5. Schroff, M.L.,
Inorganic Pharmaceutical Chemistry. New Delhi: Oxford Book Company.
6. Indian
Pharmacopoeia Commission, Indian Pharmacopoeia. Ghaziabad, India.