Demulcents are inert substances which sooth inflamed/denuded mucosa or skin by preventing contact with air/irritants in the surroundings. They are, in general, high molecular weight substances and are applied as thick colloidal/ viscid solutions in water.
DEMULCENTS
Demulcents are inert
substances which sooth inflamed/denuded mucosa or skin by preventing contact
with air/irritants in the surroundings. They are, in general, high molecular
weight substances and are applied as thick colloidal/ viscid solutions in
water. Some, like gum acacia, gum tragacanth produce foam with water,
reduce surface tension and act as suspending/emulsifying
agents.
Glycyrrhiza is a sweet tasting
root (liquorice); used in cough
lozenges to sooth the throat and as sweetening/flavouring agent in mixtures. It
contains a glycoside glycyrrhizin
which has steroid like salt retaining action when taken orally.
Methylcellulose It is a synthetic
cellulose derivative used as bulk purgative, in nose drops and contact lens
solutions.
CADILOSE 0.5% drops in
10 ml bottle.
Propylene glycol is a clear, viscous
liquid, miscible with water as well
as some oils that is used in cosmetics and as occlusive dressing for
ichthyosis, etc.
Glycerine is a clear, sweet,
viscous liquid. Undiluted glycerine
has dehydrating property— produces a warm sensation and irritates mucous
membranes. Applied to anal canal as suppository it induces evacuation. Applied
to dry skin and cracked lips (50% in water) it acts as emollient and is a
popular vehicle for gum/throat paints. It is also used orally/per rectum
(50–75%) or intravenously (10%) to reduce intraocular/ intracranial tension.
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