Quetiapine (Placidin, Q-Pin, Pincalm)

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Chapter: Medicinal Chemistry : Tranquillizers

Quetiapine (Placidin, Q-Pin, Pincalm) - SYNTHESIS AND DRUG PROFILE - Structure, Properties, uses, Synthesis, Assay, Storage, Dosage forms, Dose | Synthesis and Drug Profile


SYNTHESIS AND DRUG PROFILE


Miscellaneous


Quetiapine (Placidin, Q-Pin, Pincalm)


Synthesis


Properties and uses: It exists as white crystals. Quetiapine is used orally to treat psychotic disorders and symptoms, such as hallucinations, delusions, and hostility.

Dose: For Schizophrenia: Adult: Initially, 25 mg twice a day on day 1 increased to 50 mg twice a day on day 2, 100 mg twice a day on day 3, and 150 mg twice a day on day 4. Usual dose range: 300–450 mg daily. Maximum: 750 mg/day, For elderly: Initially, 25 mg daily, increased in steps of 25–50 mg daily according to response.


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