Classification - Glycosides

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Chapter: Pharmacognosy and Phytochemistry : Drugs Containing Glycosides

The glycosides can be classified by the glycone, by the type of glycosidal linkage, and by the aglycone.


CLASSIFICATION

 

 

The glycosides can be classified by the glycone, by the type of glycosidal linkage, and by the aglycone.

 

On the Basis of Glycone

 

If the glycone group of a glycoside is glucose, then the molecule is a glucoside; if it is fructose, then the molecule is a fructoside; if it is glucuronic acid, then the molecule is a glucuronide, etc.

 

On the Basis of Glycosidic Linkage


1.     O-glycosides: Sugar molecule is combined with phenol or –OH group of aglycon, for example, Amygd-aline, Indesine, Arbutin, Salicin, cardiac glycosides, anthraxquinone glycosides like sennosides etc

2.     .

3.     N-glycosides: Sugar molecule is combined with N of the –NH (amino group) of aglycon, for example, nucleosides

 

4.     S-glycosides: Sugar molecule is combined with the S or SH (thiol group) of aglycon, for example, Sinigrin.

 

5.     C-glycosides: Sugar molecule is directly attached with C—atom of aglycon, for example, Anthraquinone glycosides like Aloin, Barbaloin, Cascaroside and Flavan glycosides, etc.

 

On the Basis of Aglycone

 

The various classes according to aglycone moiety are given below:

 


 

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