Transdermal Androgen
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Recently delivery of androgen across skin has been achieved by developing suitable solvents and absorption facilitators. By cutaneous delivery, testosterone/dihydrotestosterone circumvent hepatic first pass metabolism; uniform blood levels are produced round the clock.
TRANSDERMAL ANDROGEN
Recently
delivery of androgen across skin has been
achieved by developing suitable solvents and absorption facilitators. By
cutaneous delivery, testosterone/dihydrotestosterone circumvent hepatic first
pass metabolism; uniform blood levels are produced round the clock. A gel
formulation has been marketed for once daily application in hypogonadism and
impotence.
ANDRACTIM:
Dihydrotestosterone 25 mg/g gel (100 g tube); 5–10 g gel to be
applied over nonscrotal skin once daily.
Fixed
dose combinations of testosterone with yohimbine, strychnine and vitamins are
banned in India.
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