Antifungal Agents

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Chapter: Medicinal Chemistry : Antifungal Agents

Human-fungi-parasitic relationship result in mycotic illnesses. Most fungal infections (mycoses) involve superficial invasion of the skin or mucous membrane of the body orifices.


Antifungal Agents

Human-fungi-parasitic relationship result in mycotic illnesses. Most fungal infections (mycoses) involve superficial invasion of the skin or mucous membrane of the body orifices. These diseases can usually be controlled by local application of the antifungal agents. Fungi have different shapes and sizes. Some are large while others are minute, parasitic, and saprophytic cells. They differ from the following organisms in some important aspects:

·Algae by lack of photosynthetic ability.

·Protozoa by the lack of motility, possession of chitinuous cell wall, and ease of culture on simple media.

·Bacteria by greater size and having certain intracellular structure such as mitochondria and nuclear membrane.

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