Introduction to Medicinal Chemistry

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Chapter: Medicinal Chemistry : Introduction to Medicinal Chemistry

Medicinal chemistry is a discipline at the intersection of chemistry and pharmacology that involves the identification, synthesis, and development of new chemical entities that are suitable for medical or pharmaceutical use.


Introduction to Medicinal Chemistry

Medicinal chemistry is a discipline at the intersection of chemistry and pharmacology that involves the identification, synthesis, and development of new chemical entities that are suitable for medical or pharmaceutical use. Medicinal chemistry is an interdisciplinary science combining variety of subjects such as organic chemistry, phytochemistry, pharmacology, toxicology, molecular biology, biochemistry, computational chemistry, physical chemistry, and statistics. It also includes the study of existing drugs, their pharmacological properties, toxic effects, and their quantitative structure-activity relationships (QSARs).

Majority of the medicinal compounds, which are used as medicines are natural products and synthetic organic compounds. However, metal-containing compounds are also found to be useful as drugs. For example, cisplatin series of platinium-containing complexes are used as anticancer agents. These compounds are known as metal-based drugs.

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