Adverse Effects and Contraindications - Adrenergic Drugs

ADVERSE EFFECTS AND CONTRAINDICATIONS

·        Transient restlessness, palpitation, anxiety, tremor, pallor may occur after s.c./i.m. injection of Adr.

·        Marked rise in BP leading to cerebral haemorrhage, ventricular tachycardia/fibrillation, angina, myocardial infarction are the hazards of large doses or inadvertant i.v. injection of Adr.

·        Adr is contraindicated in hypertensive, hyperthyroid and angina patients.

·        Adr should not be given during anaesthesia with halothane (risk of arrhythmias) and to patients receiving β blockers (marked rise in BP can occur due to unopposed α action).