Biotechnology in the Pharmaceutical Industry
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One of the first and most important commercial applications of genetic engineering was the introduction of genes coding for clinically important proteins into bacteria. Because bacterial cells are cheap to grow on a large scale in fermenters, they can synthesize vast amounts of protein from the recombinant genes they carry.
BIOTECHNOLOGY IN THE
PHARMACEUTICAL INDUSTRY
One of the first
and most important commercial applications of genetic
engineering was the introduction of genes coding for clinically important proteins into bacteria. Because bacterial cells are cheap
to grow on a large scale in fermenters, they can synthesize vast amounts of protein from the recombinant genes
they carry. This results in a significant reduction in cost and
an increase in the availability of these proteins. There are currently a large
number of important recombinant drugs available on the market,
examples of which
are provided in Table 25.5. This chapter covers
only the genetic
manipulation strategies used
to produce some
well-known drugs.
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