Imidazole Alkaloids

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Chapter: Pharmacognosy and Phytochemistry : Drugs Containing Alkaloids

Imidazole is a heterocyclic aromatic organic compound. This ring system is present in important biological build-ing blocks such as histidine and histamine. Imidazoles can act as bases (Pka = 7.0) and as a weak acids (pK = 14.5). Imidazole exists in two tautomeric forms with a hydrogen atom moving between the two nitrogens.


IMIDAZOLE ALKALOIDS

 

 

Imidazole is a heterocyclic aromatic organic compound. This ring system is present in important biological build-ing blocks such as histidine and histamine. Imidazoles can act as bases (Pka = 7.0) and as a weak acids (pK = 14.5). Imidazole exists in two tautomeric forms with a hydrogen atom moving between the two nitrogens.

 

The most important plant of this group is Pilocarpus jaborandi.

 

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