Classification of Amoebicides

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Chapter: Medicinal Chemistry : Antiamoebic Agents

I. Luminal amoebicides II. Systemic amoebicides III. Mixed amoebicides


CLASSIFICATION OF AMOEBICIDES

I.           Luminal amoebicides: Diloxanide furoate.

It is active only against intestinal forms of amoeba.

II.         Systemic amoebicides: Dihydroemetin, Choroquine.

These agents have been employed primarily to treat severe amoebic dysentery or hepatic abscesses.

III.      Mixed amoebicides: Metronidazole, tinidazole, and ornidazole.

These agents are active against both intestinal and systemic forms of amoeba.

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