Dihydro indolones

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Chapter: Medicinal Chemistry : Tranquillizers

Dihydro indolones - SYNTHESIS AND DRUG PROFILE - Dihydro indolones - Structure, Properties, uses, Synthesis, Assay, Storage, Dosage forms, Dose | Synthesis and Drug Profile


SYNTHESIS AND DRUG PROFILE


Dihydro indolones


a. Molindone (Liclone, Moban)


Synthesis


Properties and uses: Exists as white crystals, freely soluble in water or alcohol, it is a potent antipsychotic as trifluoperazine and all the side effects resemble those of the phenothiazines. It is used in the treatment of schizophrenia and other psychosis.

Dose: The usual dose is 15–25 mg/day.


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