Fourth-generation cephalosporin

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Chapter: Medicinal Chemistry : Antibiotics

Fourth-generation cephalosporin : Cefpirome (Ceform, Ominorm, Taform)


Cephalosporins - Synthesis and Drug Profile

Fourth-generation cephalosporin

 

i. Cefpirome (Ceform, Ominorm, Taform)


Synthesis


Properties and uses: Cefpirome is used to treat susceptible infections, including urinary and respiratory tract infections, skin infections, septicaemia, and infections in immuno-compromised patients.

Dose: Intravenous dose for adults as sulphate is 1–2 g every 12 h over 3–5 min or infuse over 20–30 min.

 

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