Biosynthesis of Glycosides

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Chapter: Pharmacognosy and Phytochemistry : General Biosynthetic Pathways of Secondary Metabolites

The glycosides are the condensation products of sugar and the acceptor unit called as aglycone. The reaction occurs in two parts as given below. Firstly sugar phosphates bind with uridine triphosphate (UTP) to produce sugar—uridine diphosphate sugar complex. This sugar nucleotide complex reacts with acceptor units in the second reaction which leads to glycoside production.


BIOSYNTHESIS OF GLYCOSIDES

 

 

The glycosides are the condensation products of sugar and the acceptor unit called as aglycone. The reaction occurs in two parts as given below. Firstly sugar phosphates bind with uridine triphosphate (UTP) to produce sugar—uridine diphosphate sugar complex. This sugar nucleotide complex reacts with acceptor units in the second reaction which leads to glycoside production.

 


 

Once such glycosides are formed, other specific enzymes may transfer another sugar unit in the later reactions in which the glycoside formed in the previous reaction work as an acceptor to provide di-, tri-, or tetraglycosides and so on by subsequent reactions.

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