Microscopy of Organisms of Pharmaceutical and Medical Significance
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Observation of stained and wet preparations of clinical specimens (blood, pus, sputum) and isolated pure cultures of bacteria from the manufacturing environment provides rapid and essential information to guide further identification.
MICROSCOPY OF ORGANISMS OF PHARMACEUTICAL AND MEDICAL SIGNIFICANCE
Observation of stained
and wet preparations of clinical specimens (blood, pus, sputum) and isolated
pure cultures of bacteria from the manufacturing environment provides rapid and
essential information to guide further identification. The application of
simple stains such as the Gram stain can divide the various genera of bacteria
into two convenient broad groups. The size and shapes of individual cells and
their arrangement into clusters, chains and tetrads will also guide
identification, as will specific stains for the presence of endospores,
capsules, flagella and inclusion bodies. Examination of wet preparations can
give an indication as to the motility status of the isolate, and these
procedures all represent an important first stage in the identification
process.
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