Classification of Diuretics

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Chapter: Medicinal Chemistry : Diuretics

Diuretics may be classified under the following two categories: I. Mercurial diuretics II. Nonmercurial diuretics


CLASSIFICATION

Diuretics may be classified under the following two categories:


I. Mercurial diuretics



II. Nonmercurial diuretics

The nonmercurial diuretics may be classified on the basis of their chemical structure as follows:

a. Thiazide derivatives


b. Hydrothiazides


c. CAse inhibitors


d. Sulphonamide diuretics


e. Aldosterone inhibitors



f. Pteridine derivatives and related compounds


g. sulphomoyl benzoic acid derivatives


h. Phenoxyacetic acid derivatives


i. Purine or Xanthine derivatives



j. Osmotic diuretics

Sodium and potassium salt, urea, sucrose, mannitol, trometamol, sodium acid phosphate, potassium acetate, and glycerine are the osmotic diuretics.


k. Acidic diuretics

Ammonium chloride is a acidic diuretic.

l. Uricosuric diuretics

i. Indacrinone


m. Miscellaneous

Example: Muzolimine


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