Prescription–event monitoring (PEM) is a valuable and well-established method of hypothesis-generating pharmacovigilance.
CONCLUSION
Prescription–event
monitoring (PEM) is a valuable and well-established method of
hypothesis-generating pharmacovigilance. Its use since 1984 has produced a
substantial database which itself forms an important research tool. PEM has
found its own place in phar-macovigilance and is at its best in monitoring
drugs receiving widespread, long-term GP use. The method lends itself to
validation of individual case reports and allows the data to be explored by
well-established epidemiological and clinical research techniques.
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