The discipline of pharmacovigilance has developed and improved over the years.
CONCLUSIONS
The
discipline of pharmacovigilance has developed and improved over the years. Much
information on drug safety is now collected and subject to expert analysis and
review. However, drug-induced morbidity remains a leading cause of hospital
admis-sion in several countries. Many improvements have been mentioned, but the
primary immediate need is for effective and efficient communication to health
professionals.
This
will need a paradigm shift from a gaze focused only on finding novel ADRs to
new drugs, to a concentration on finding the problems associated with drug use
in the community and how to improve it. Feedback on the results of efforts to
improve the ther-apy of patients in regular clinical practice is essential for
the future.
Health
professions are criticised for many deficien-cies, one of which is drug-related
injury, but in our view, society does not equip the health professions with the
right resources to improve their performance. On the contrary, health
professionals work under increasingly difficult circumstances in many
coun-tries. As far as drug safety is concerned, the provision of much better
information for health professionals and the time for them to analyse and use
the informa-tion is the main challenge for the near future. Only then can
patients feel that they have the best chance of rational, individually tailored
treatment, the best chance of not experiencing ADRs, the best chance of having
unavoidable ADRs diagnosed and the best chance of important clinical
experiences of ADRs being reported and used for future improvements.
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