Echinocandins-Caspofungin, Anidulafungin and Micafungin
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These members of the echinocandin group of antifungal agents have been developed for treatment of serious fungal infections. They interfere with the synthesis of the β-1,3-d-glucan polymer in the fungal cell wall.
ECHINOCANDINS—CASPOFUNGIN, ANIDULAFUNGIN AND MICAFUNGIN
These members of the echinocandin group of antifungal agents have been
developed for treatment of serious fungal infections. They interfere with the
synthesis of the β-1,3-d-glucan polymer in the fungal cell wall. Without the
glucan polymer, the integrity of the fungal cell wall is compromised, yeast
cells lose their rigidity and become like protoplasts; the effect is especially
pronounced in Candida and Aspergillus species.
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