Advantages of pharmaceutical dosage forms

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Chapter: Pharmaceutical Drugs and Dosage: Pharmaceutical considerations

A pharmaceutical dosage form is the entity that is administered to patients so that they receive an effective dose of a drug.


Advantages of pharmaceutical dosage forms

A pharmaceutical dosage form is the entity that is administered to patients so that they receive an effective dose of a drug. Some common examples are tablets, capsules, suppositories, injections, suspensions, and transder-mal patches. Besides providing the mechanism for the safe and convenient delivery of accurate dosage, pharmaceutical dosage forms are needed for the following additional reasons:

·           To protect the drug substance from the destructive influence of atmo-spheric oxygen or humidity (coated tablets).

·           To protect the drug substance from the destructive influence of gastric acid after oral administration (enteric-coated tablets).

·           To conceal the bitter, salty, or offensive taste or odor of a drug sub-stance (capsules, coated tablets, and flavored syrup).

·           To provide liquid preparations of substances that are either insoluble or unstable in the desired vehicle (suspensions).

·           To provide rate-controlled drug action (various controlled-release tables, capsules, and suspensions).

·           To provide site-specific and local drug delivery (e.g., rectal and vagi-nal suppositories).

·           To target the drug at the desired site of action (e.g., nanoparticulate systems, liposomes, etc.).

 

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