Both N-1 and N-4 substituted sulphonamides : i. Succinyl sulphathiazole ii. Phthalyl Sulphathiazole (Thalazole)
Both N-1 and N-4 substituted sulphonamides
Synthesis
Uses: Used in bacillary dysentery and cholera.
Dose: Dose is 10–20 g per day in divided doses.
Synthesis
Properties and uses: Slightly soluble in alcohol and ether, but
insoluble in water. It is used in the treatment of acute bacillary dysentery,
bowel irregularities, and ulcerative colitis.
Dose: Dose is 5–10 g per day in divided doses.
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