I. Benzoic acid derivatives II. p-Amino benzoic acid derivatives III. Anilide derivatives (2,6 Xylidines) IV. Miscellaneous
CLASSIFICATION Local anaesthetics are generally classified into the following groups : Natural agents Cocaine Synthetic nitrogenous compounds Derivatives of benzoic acid Derivatives of para-amino benzoic acid Freely soluble: Procaine, Amethocaine. Poorly soluble: Benzocaine, Orthocaine Derivatives of acetanilide: Lignocaine, Mepivacaine, Bupivacaine, Prilocaine, Etidocaine. Derivatives of quinoline: Cinchocaine, dimethisoquin Synthetic non-nitrogenous agents: Benzyl alcohol, propanediol Miscellaneous drugs with local action: Clove oil, phenol, chlorpromazine and certain antihistamines, for example, diphenhydramine On the basis of chemical structure, local anaesthetics are classified as follows: I. Benzoic acid derivatives II. p-Amino benzoic acid derivatives III. Anilide derivatives (2,6 Xylidines) IV. Miscellaneous
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