Essentials of Inorganic Chemistry : Radioactive Compounds and Their Clinical Application - Exercises and Case studies
Exercises
1. Write the
elemental formula for the following radioisotopes:
(a)
Technetium containing 48 neutrons
(b)
Radon containing 136
(c)
Francium containing 136 neutrons
(d)
Radium containing 138 neutrons
2. Write the
equation for the radioactive decay of the following elements:
(a)
210Po (α-emitter)
(b)
226Ra (α-emitter)
(c)
91Tc (β-emitter –
positron)
(d)
227Ac (β-emitter –
negatron)
3. A 201Tl
chloride injection has a labelled activity of 450 Ci. Express this answer in
megabec-querel.
4. A
radioactive material has an activity of 12.25 mCi. How many disintegrations per
second are represented by this?
5. A
radioactive material has been labelled with an activity of 112 MBq. Convert
this activity into curie.
6. If a
radioactive element has a half-life of 2 h, what percentage of material is left
after
(a)
2 h
(b)
6 h
(c)
8 h
7. The
disintegration constant of 24Na is 0.0462 year−1. Determine the half-life of this radioisotope.
1. A
sample containing 99mTc was found to have a radioactivity of 15 mCi
at 8 a.m. when the sample was tested.
(a)
Research the half-life of 99mTc.
(b)
Calculate its activity at 5 a.m. on the same
day, when it was prepared.
(c)
Calculate its activity at 3 p.m. on the same
day, when it was administered to the patient.
State your answer in curies and SI units.
2. A
typical intravenous dose of 99mTc-albumin used for lung imaging contains
a radioactivity of 4 mCi
(a)
Convert the dose to SI unit.
(b)
What radioactive dose is left after 12 h, when
the technetium is cleared from the body?
(c)
The pharmacist prepared the sample actually 2
h before the administration. What activity did this sample have at that point
of preparation?
(d)
The pharmacist prepared a 2 ml solution for
injection. What is the activity concentration at the point of administration?
3. Develop
a quick-reference radioactive decay chart for 131I
Research the half-life of 131I and calculate the
percentage activity remaining for 20 days using 1-day intervals.
Create your own quick-reference radioactive
decay chart.
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