Hormonal Contraceptives

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Chapter: Essential pharmacology : Estrogens, Progestins and Contraceptives

These are hormonal preparations used for reversible suppression of fertility. Because of our alarming population trends, antifertility drugs are the need of the day. In developing countries particularly, the mortality rate has declined and birth rate has increased due to urbanization.


HORMONAL CONTRACEPTIVES

 

These are hormonal preparations used for reversible suppression of fertility. Because of our alarming population trends, antifertility drugs are the need of the day. In developing countries particularly, the mortality rate has declined and birth rate has increased due to urbanization. In the earlier part of 20th century, methods of contraception used (condoms, diaphragms, spermicidal creams, foam tablets, etc.) were intimately related to sexual intercourse, therefore, despised by most couples. These also have higher failure rate. Rock and Pincus (1955) announced the successful use of an oral progestin for contraception, separating fertility control from coitus.

 

It was soon discovered that addition of a small quantity of an estrogen enhanced their efficacy; combined pills have become the most popular method of contraception, particularly because the hormone content of the pills has been reduced, minimizing the potential harm and affording other health benefits.

 

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