Classification of Anthelmintics

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Chapter: Medicinal Chemistry : Anthelmintics

The anthelmintic agents comprise of drugs of chemically diverse structures and their mechanism of action differs from one agent to another.


CLASSIFICATION

The anthelmintic agents comprise of drugs of chemically diverse structures and their mechanism of action differs from one agent to another.

 

I. Benzimidazoles

These are versatile anthelmintic agents particularly effective against gastrointestinal nematodes. These are highly effective against ascaris, enterobius, trichuris, and hookworm infections as single or mixed infections.


 

II. Quinolines and isoquinolines

Oxamniquine


Praziquantel


 

III. Piperazine derivatives

Piperazine citrate


Diethyl carbmazine


 

IV. Vinyl pyrimidines

Pyrantel pamoate


Oxantel

 

V. Amides

Niclosamide



VI. Natural products: Avermectins

VII. Organo phosphorus: Metrifonate

VIII. Imidazothiazoles: Levamisole

IX. Nitro derivatives: Niridazole.

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