Coagulants: In vitro anticoagulants - i. Sodium citrate ii. Sodium oxalate - Synthesis and Drug Profile
SYNTHESIS AND DRUG PROFILE
Synthesis
Properties and uses: Sodium citrate exists as white crystalline
powder or granular crystals, soluble in water, but insoluble in alcohol and
used as systemic alkalinizing substance.
Assay: Dissolve the sample in anhydrous acetic acid. Heat it, allow to
cool and titrate against 0.1 M perchloric acid using naphtholbenzein as
indicator until a green colour is obtained.
Dosage forms: Sodium citrate eye drops B.P., Sodium citrate irrigation
solution B.P.
Synthesis
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