Diarrhoea means loose bowel movements resulting into the frequent passage of watery, uniformed stools with or without mucous and blood.
Drugs Acting on Digestive System
Antidiarrhoeals
Diarrhoea
means loose bowel movements resulting into the frequent passage of watery,
uniformed stools with or without mucous and blood. This condition may arise due
to the change in the nature of the diet and routine or sometimes due to
bacterial infection. The former type of diarrhoea is the mild form while the
infective diarrhoea is more powerful and persistent. Organism escapes from
gastric acid and other digestive processes reaches the bowel. Their metabolic
products irritate the nerve ending of intestinal wall leading to severe
diarrhoea. In this condition, to compensate the loss of body fluids, a mixture
of salt (sodium chloride or sodium bicarbonate) and water is to be given
frequently. The simple type of diarrhoea may be controlled just by using
intestinal adsorbents while infected diarrhoea needs the use of intestinal
antiseptics.
These
substances have the power of adsorbing gases, bacteria, and toxins without
undergoing any chemical reaction. They also posses the protective property
apart from their adsorbent action. They form a coating over the intestinal
mucosa to reduce its irritation, example of this category are kaolin, calcium
carbonate, magnesium trisilicate, and aluminium hydroxide, pectin, bismuth
subsalicylate and polycarbophill and various psyllium seed derivatives.
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