Local drug delivery to the lung
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Pulmonary route has long been utilized for localized drug delivery to the lung, which helps overcome several barriers to the treatment of lung disorders such as systemic side effects and metabolism, while allowing high local concentrations and rapid clinical response.
Local drug
delivery to the lung
Pulmonary
route has long been utilized for localized drug delivery to the lung, which
helps overcome several barriers to the treatment of lung disorders such as
systemic side effects and metabolism, while allowing high local concentrations
and rapid clinical response. In many cases, the dose of the drug required for
local treatment can be significantly reduced. For example, orally administered
salbutamol at 2–4 mg of dose is therapeutically equiva-lent to 100–200 μg of salbutamol administered
directly into the lung.
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