Excretion of Drugs
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Drugs and/or their metabolites are removed from the body by excretion.
Excretion
of Drugs
Drugs and/or their metabolites are removed from the
body by excretion. Excretion is defined as the process whereby drugs and/or their metabolites are irreversibly
transferred from internal to external environment. Excretion of unchanged
or intact drug is important in the termination
of its pharmacological action. The principal organs of excretion are kidneys.
Excretion of drug by kidneys is called as renal
excretion. Excretion by organs other
than kidneys such as lungs, biliary
system, intestine, salivary glands and sweat glands is known as nonrenal excretion.
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