Production of Very Fine Crystals

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Chapter: Pharmaceutical Engineering: Crystallization

Fine powders are important components in pharmaceutical operations.


PRODUCTION OF VERY FINE CRYSTALS

Fine powders are important components in pharmaceutical operations. If a substance has a steep solubility curve, fine crystals are produced by quickly cooling the solution through the metastable region to conditions in which the rate of nucleation is high and the rate of crystal growth is low. This method is not always possible, and the precipitation methods described above may be adopted.

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