Clinical Pharmacy and Drug Interactions

Pharmacology: Clinical Pharmacy and Drug Interactions - Covers all topics with images and clear explanation. Study Clinical Pharmacy and Drug Interactions (Pharmacology) Online course, study material, important questions and answers, Notes, textbook.


Clinical Pharmacy and Drug Interactions




PART I: INTRDUCTORY CHAPTERS



Chapter 1: Drug discovery


=> Drug discovery
=> Collaborating disciplines
=> Small - versus large-molecule paradigms
=> Contemporary drug discovery case studies
=> Summary and outlook to the future
=> Review questions and answers

Chapter 2: Drug development


=> Drug development
=> Stage-gate process of new drug discovery and development
=> Pharmaceutical development
=> Regulatory approval
=> Postcommercialization activities
=> Review questions and answers

Chapter 3: Pharmaceutical considerations


=> Pharmaceutical considerations
=> Advantages of pharmaceutical dosage forms
=> Influential factors in dosage form design
=> Review questions and answers

Chapter 4: Biopharmaceutical considerations


=> Biopharmaceutical considerations
=> Diffusion: Drug transport across a polymeric barrier
=> Principles of diffusion
=> Diffusion rate
=> Dissolution
=> Absorption
=> Review questions and answers

Chapter 5: Pharmacy math and statistics


=> Pharmacy math and statistics
=> Systems of measure
=> Ratio and proportion
=> Concentration calculations
=> Clinical dose calculations
=> Statistical measures
=> Tests of statistical significance
=> Review questions and answers

PART II: PHYSICOCHEMICAL PRINCIPLES



Chapter 6: Complexation and protein binding


=> Complexation and protein binding
=> Types of complexes
=> Protein binding
=> Review questions answers

Chapter 7: Chemical kinetics and stability


=> Chemical kinetics and stability
=> Reaction rate and order
=> Factors affecting reaction kinetics
=> Drug degradation pathways
=> Stabilization strategies
=> Review questions answers

Chapter 8: Interfacial phenomena


=> Interfacial phenomena
=> Liquid–liquid and liquid-gas interfaces
=> Solid-gas interface: Adsorption
=> Solid-Liquid interface
=> Biological and pharmaceutical applications
=> Review questions answers

Chapter 9: Colloidal dispersions


=> Colloidal dispersions
=> Types of colloidal systems
=> Preparation of colloidal solutions
=> Properties of colloidal solutions
=> Physical stability of colloids
=> Review questions answers

Chapter 10: Surfactants and micelles


=> Surfactants and micelles
=> Surfactants
=> Types of surfactants
=> Hydrophile-lipophile balance system
=> Micelles
=> Factors affecting critical micelle concentration and micellar size
=> Micellar solubilization
=> Review questions answers

Chapter 11: Pharmaceutical polymers


=> Pharmaceutical polymers
=> Definitions and architectures of polymers
=> Polymer molecular weight and weight distribution
=> Biodegradablity and biocompatibility
=> Physicochemical properties and solubility
=> Block copolymers
=> Intelligent or stimuli-sensitive polymers
=> Water-soluble polymers
=> Bioadhesive/mucoadhesive polymers
=> Review questions answers

Chapter 12: Rheology


=> Rheology
=> Newtonian flow
=> Non-Newtonian flow
=> Thixotropy
=> Pharmaceutical applications of rheology
=> Review questions answers

Chapter 13: Radiopharmaceuticals


=> Radiopharmaceuticals
=> Biomedical applications of radiopharmaceuticals
=> Radiation detection equipment
=> Formulation of radiopharmaceuticals
=> Calculations of Radiopharmaceuticals
=> Review questions answers

Chapter 14: Drug delivery systems


=> Drug delivery systems
=> Targeted drug delivery
=> Prodrugs
=> Soluble macromolecular carriers
=> Particulate carrier systems
=> Oral drug delivery
=> Alternative routes of delivery
=> Review questions answers

Chapter 15: Organ-specific drug delivery


=> Organ-specific drug delivery
=> Need for alternate, nonoral routes to the systemic circulation
=> Need for organ specific and targeted drug delivery
=> Local drug delivery to the lung
=> Systemic drug delivery through the lung
=> Devices for pulmonary drug delivery
=> Ocular drug delivery
=> Brain targeted drug delivery
=> Liver-targeted drug delivery
=> Colon-targeted drug delivery
=> Combination and other strategies for colon targeting
=> Review questions answers

PART III: DOSAGE FORMS



Chapter 16: Suspensions


=> Suspensions
=> Types of suspensions
=> Powder for suspension
=> Quality attributes
=> Formulation considerations
=> Manufacturing process
=> Review questions answers

Chapter 17: Emulsions


=> Emulsions
=> Types of emulsions
=> Quality attributes
=> Formulation considerations
=> Emulsification
=> Manufacturing process
=> Stability
=> Review questions answers

Chapter 18: Pharmaceutical solutions


=> Pharmaceutical solutions
=> Types of solutions
=> Quality attributes
=> Formulation components and manufacturing process
=> Solubility
=> Stability
=> Review questions answers

Chapter 19: Powders and granules


=> Powders and granules
=> Production of powders and granules
=> Analyses of powders
=> Particle shape and size - Analyses of powders
=> Surface area - Analyses of powders
=> Density and porosity - Analyses of powders
=> Flow - Analyses of powders
=> Compactibility - Analyses of powders
=> Content uniformity - Analyses of powders
=> Powder processing
=> Powders as dosage forms
=> Review questions answers

Chapter 20: Tablets


=> Tablets
=> Types of tablets
=> Tablet formulation
=> Manufacturing of tablets
=> Evaluation of tablets
=> Relationship among disintegration, dissolution, and absorption
=> Review questions answers

Chapter 21: Capsules


=> Capsules
=> Hard gelatin capsules
=> Soft gelatin capsules
=> Evaluation of capsule drug products
=> Shelf-life tests
=> Review questions answers

Chapter 22: Parenteral drug products


=> Parenteral drug products
=> Parenteral routes of administration
=> Types of parenteral dosage forms
=> Quality attributes and evaluation
=> Formulation components
=> Sterilization
=> Review questions answers

Chapter 23: Semisolid dosage forms


=> Semisolid dosage forms
=> Ointments and Types of ointment bases
=> Creams
=> Gels and jellies
=> Lotions
=> Pastes
=> Foams
=> Manufacturing processes
=> Analysis of semisolid dosage forms
=> Review questions answers

Chapter 24: Inserts, implants, and devices


=> Inserts, implants, and devices
=> Ocular inserts, Suppositories, Vaginal rings
=> Implants and Types of implants
=> Devices
=> Review questions answers

Chapter 25: Protein and peptide drug delivery


=> Protein and peptide drug delivery
=> Structure of Proteins and peptides
=> Types of protein and peptide therapeutics
=> Protein characterization
=> Instability
=> Antigenicity and immunogenicity
=> Drug product formulation and process
=> Review questions answers

Chapter 26: Biotechnology-based drugs


=> Biotechnology-based drugs
=> Gene and gene expression
=> Gene silencing
=> Gene silencing technologies
=> Gene therapy
=> Review questions answers

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